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Deze Concept Map heeft informatie gerelateerd aan: Zonder titel, Antibodies (mainly IgG) Cross-reaction with GM1, GD1a, Campylobacter jejuni (CSTII gene) LOS binds to Siglec-7, Disapperance Na+ channels Leads to Demyelination and vascular degeneration, MAC formation Leads to Demyelination and vascular degeneration, Nodal axolemma at or near node of Ranvier Complement activation Disapperance Na+ channels, Antibodies (mainly IgG) Cross-reaction with GQ1b, GD1b, GD3, GT1a, Myeline sheath (?) on Schwann cell Complement activation Disapperance Na+ channels, Antibodies (mainly IgG) Cross-reaction with Various (unknown), GQ1b, GD1b, GD3, GT1a On Muscle spindles, Type 1 interferon and TNF Induce proliferation B-Cells, Demyelination and vascular degeneration Leads to Invasion macrophages, Muscle spindles in Facial muscles, Plasma cells Secrete Antibodies (mainly IgG), MAC formation Leads to Detachment paranodal myeline, nerve conduction failure and axon terminal degeneration, Disapperance Na+ channels Leads to Detachment paranodal myeline, nerve conduction failure and axon terminal degeneration, Detachment paranodal myeline, nerve conduction failure and axon terminal degeneration Leads to Invasion macrophages, Siglec-7 Activation DC with TLR4 and CD14, Various (unknown) On Myeline sheath (?) on Schwann cell, Nodal axolemma at or near node of Ranvier Complement activation MAC formation, Myeline sheath (?) on Schwann cell Complement activation MAC formation