FreeCalc sample size estimation Inputs Test sensitivity 0.975 Test specificity 0.995 Population size 1,00E+06 Design prevalence 0.05 Diseased elements 50000 Analysis method Simple binomial (large population) Target Type I error 0.05 Target Type II error 0.05 Population threshold for infinite probability formula 10000 Maximum sample size 3200 Results Required sample size: 116 Cut-point number of reactors: 2 Type I error: 0.049 Type II error: 0.0209 Herd-level sensitivity: 0.951 Herd-level specificity: 0.9791 Interpretation: If a random sample of 116 units is taken from a population of 1e+06 and 2 or fewer reactors are found, the probability that the population is diseased at a prevalence of 0.05 is 0.049. Method: Simple binomial (large population) Detailed Results 1 1 0.0535 0.995 0 0.9465 0.005 2 100 0.908 0.9859 2 0.092 0.0141 3 200 0.9948 0.9813 3 0.0052 0.0187 4 101 0.9115 0.9855 2 0.0885 0.0145 5 102 0.9148 0.9851 2 0.0852 0.0149 6 103 0.9181 0.9847 2 0.0819 0.0153 7 104 0.9212 0.9843 2 0.0788 0.0157 8 105 0.9242 0.9839 2 0.0758 0.0161 9 106 0.9271 0.9835 2 0.0729 0.0165 10 107 0.9299 0.9831 2 0.0701 0.0169 11 108 0.9326 0.9827 2 0.0674 0.0173 12 109 0.9352 0.9823 2 0.0648 0.0177 13 110 0.9377 0.9819 2 0.0623 0.0181 14 111 0.9401 0.9814 2 0.0599 0.0186 15 112 0.9425 0.981 2 0.0575 0.019 16 113 0.9447 0.9805 2 0.0553 0.0195 17 114 0.9469 0.9801 2 0.0531 0.0199 18 115 0.949 0.9796 2 0.051 0.0204 19 116 0.951 0.9791 2 0.049 0.0209