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This Concept Map, created with IHMC CmapTools, has information related to: MHC complexes cMAP, PBGs peptide length 12-17 AAs, MHCs fxns Selectively Bind Peptides (selectivity < Abs & TCRs), Polygenicity 2 subinits -alpha -beta, T cells binds to MHC MHC-II, MHC-II features Polygenicity, MHC-II features Chromosome 6, -Exogenous Ag -Const. Expressed on APCs -Interacts with CD4 synthesize Cytokines, Superantigens Ag binds OUTSIDE PBG (non-specific), -Endogenous Ag -Nucleated Cells -Interacts w/CD8 kill infected cell, Present peptide on cell surface purpose Recognition by TCRs, PBGs peptide length 8-9 AAs, -DR -DQ -DP co-dominantly expressed 3 haplotypes per parent, Polygenicity 2 HLA genes 2 diff genes (A & B), MHC-I features Polygenicity, A,B,C 1 protein per gene 3 haplotypes per parent, 2 diff genes (A & B) co-dominantly expressed 3 haplotypes per parent, MHCs fxns Present peptide on cell surface, 3 haplotypes per parent pic, MHC-II features CLIP, MHC-I features PBGs