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This Concept Map, created with IHMC CmapTools, has information related to: COPD cMAP, Rescue Plan Prednisone, COPD lab tests Spirometry, budesonide/formoterol (symbicort) drug interactions glucocorticoids CYP3A substrates grapefruit juice, COPD signs & symptoms chronic cough, COPD signs & symptoms Chronic sputum production, COPD signs & symptoms Dyspnea, Pt's FEV1 vs predicted 50-79% GOLD 2, budesonide/formoterol (symbicort) role in COPD management reduce inflammation increase BD increase airflow to lungs, Emphysema signs Dyspnea barrel-chest, GOLD measures Pt's FEV1 vs predicted, budesonide/formoterol (symbicort) MOA anti-inflammatory glucocorticoid receptors, b2-adrenergic receptors decreased formation of mediators of inflammation: eosinophils, mast cells, macrophages, neutrophils, lymphocytes the access of sensitized T lymphocytes and macrophages to target cells may be prevented by corticosteroids, COPD treatment Rescue Plan, Pt's FEV1 vs predicted ᢈ% GOLD 1, Pharmacological inhaled steroid budesonide/formoterol (symbicort), GOLD 3 ???? inhaled steroids, COPD lab tests GOLD, COPD pathophysiology smoking, Pt's FEV1 vs predicted 30-49% GOLD 3, Rescue Plan Antibiotics, COPD pathophysiology CD8+ cells