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This Concept Map, created with IHMC CmapTools, has information related to: Last CMAP !!!, TYPE 1 HYPERSENSITIVITY PROCESS mediators Histamine, treatment ???? anti-inflammatory, Example medication ???? Corticosteroid, allergens cross link IgE's on mast cells results in obstructed airway, bronchodilators ???? beta agonists, Leukotriene antagonists ???? inflamatory mediators, TYPE 1 HYPERSENSITIVITY PROCESS ???? Early Phase (minutes), anti-inflammatory ???? mast cell stabilizer, pathophysiology leads to airway remodeling, Cysteinyl Leukotrienes release Late Phase (4+ hours), Immunomodulators decreases expression of high affinity receptors, beta agonists ???? MOA, pathophysiology allergy induced First exposure to, pathophysiology leads to airway hyperactivity, anti-inflammatory example medications Antihistamine, Classifying Sx Moderate-severe, beta agonists ???? SABA, Asthma patient 39 YOM 59", 175 lbs, Allergic Rhinitis Allergic manifestations Rhinitis Sx, Binds to H1 R (GPCR) results inhibiting binding of circulating histamine to its R