WARNING:
JavaScript is turned OFF. None of the links on this concept map will
work until it is reactivated.
If you need help turning JavaScript On, click here.
This Concept Map, created with IHMC CmapTools, has information related to: Week 12, Physiology Normal Reaction ACh, Results in Relaxed Skeletal muscle results in Increase of ACh in synapse, Cholinergic Syndrome ???? Physiology, Atropine IV adult 2-5 mg every minutes doubling initial dose, pulse increases by 25 bpm or skin flushing occurs indicates No OP toxicity, Myesthenia Gravis (MG) 20 yrs. Female 110 lbs. ???? Clinical Presentation, Results in Relaxed Skeletal muscle Drug Therapy Botox, Opening of fewer Voltage-Gated Na+ channels Results in Skeletal muscle weakness, Atropine IV children 0.05-0.1 mg/kg, ACh Receptor Down-Regulation ???? Cholinergic Syndrome, Inhibition of AChE (post synaptic neuron) Agent: Cobra Venom & Organophosphates decreases degradation of ACh, Na Channels desensitized Results in Relaxed Skeletal muscle, Physiology Abnormal Reaction ACh, Treatment muscarinic effects Atropine IV, AChE Inhibitors ???? Reversible, ACh Blocked by Anitbodies Nicontinic Receptor on Skeletal Muscle (Ligand Gated receptor), Cholinergic Syndrome ???? Treatment, Drug Therapy Maintainance Dose Oral Neostigmine 15mg tab Dose: 0.5mg/kg (AChE inhibitor), Myesthenia Gravis (MG) 20 yrs. Female 110 lbs. ???? Physiology, Modifications to Acetylcholine Action ???? Depolarization Agent: Succinylcholine