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This Concept Map, created with IHMC CmapTools, has information related to: ACE and Nic take on the bones, nicotinic receptor (voltage-gated ion channel receptor) treatment needed oximes, blocking of ligand receptor by use of depolarizing blockers, 0.1 mg/kg via IV for recommended dose required dose for 10 mg/mL vial 0.5 mL for 110 lb patient, Myesthenia Gravis (MG) symptoms droopy eyelid, Pre-synaptic terminal altered by inhibition of vesicle fusion and release of Ach, A patient walks into Pharmacy Has A droopy eyelid for 3 months, ACh from binding to active site causes excess ACh in synapse, 0.1 mg/kg via IV for initial dose requried dose for 0.5 mg/mL vial 10 mL for 110 lb patient; repeat after 5 min prn, Myesthenia Gravis (MG) pathophysiology antibodies act as competitve antagonist, Myesthenia Gravis (MG) symptoms facial paralysis, use of depolarizing blockers such as 20 mg/mL succinylcholine chloride injection, M1 receptor effect on CNS causes central respiratory depression, she gets tired/weak the longer the shake possible diagnosis Myesthenia Gravis (MG), Myesthenia Gravis (MG) symptoms fatigue, use of nondepolarizing blockers such as drugs derived from Curare Vine, A patient walks into Pharmacy Pharmacist response Shake hand, 20 mg/mL succinylcholine chloride injection 1-1.5 mg/kg for recommended dose 3.41-5.11 mL/dose for 150 lb patient, reversible or irrevesible effects can result in Overload the NM junction system with Acetylcholine, Myasthenia Gravis drugs treats by inhibiting ACh Esterase Myesthenia Gravis (MG), Modification of Acetylcholine caused by changes to Nicotinic Receptors