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This Concept Map, created with IHMC CmapTools, has information related to: Untitled, B2 agonists sympathetic activation Bronchial smooth muscle dilation, Bronchial smooth muscle dilation results opens airway and remove mucus, Acute & Chronic Asthma Clinical Presentation Hyperventilation Wheezing Chest tightness Dyspnea Can't say 3 words without being breathless Use of accessory muscles Positioned sitting upright, Tertbutaline Dosing Administer 3270 mL per hour, Tertbutaline Preparation Dilute with D5W to achieve a concentration of 0.1 mg/mL, Reduces inflammation drug used Hydrocortisone, Albuterol Sulfate dosing Inhale 1.64 mL every 6 hours, Acute & Chronic Asthma Drug Prep and Dosing Hydrocortisone, G Protein- Coupled receptors & bronchodilators Gs B2 agonists, Acute & Chronic Asthma Drug Prep and Dosing Ipratopium Bromide, Glucocorticoid receptors GR translocation Reduces inflammation, Acute & Chronic Asthma Physiology Hypoxia Hypercarbia Mucus secretion Inflammation Bronchoconstriction, Respiratory acidosis - Low pH - High PaCO2 Stage I Hyperventilation (Low PCO2 normal PO2), Acute & Chronic Asthma Drug Prep and Dosing Albuterol Sulfate, Hydrocortisone Dosing Administer 54.5 mL every 4 hours, G Protein- Coupled receptors & bronchodilators Gq Anticholinergic M1 + M3, reducing the mucus volume drugs used Ipratropium bromide Tiotropium bromide, Acute & Chronic Asthma Pharmacology Receptors Glucocorticoid receptors, Blocks the release of ACh leading to bronchodilation results reducing the mucus volume, Respiratory acidosis - Low pH - High PaCO2 Stage IV Hypoxemia with high PCO2 (Respiratory failure)