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This Concept Map, created with IHMC CmapTools, has information related to: Untitled 1, nephrotoxicity receive nephrology consult, Puppy drinks antifreeze (ethylene glycol) metabolized by alcohol dehydrogenase, (5.5 mL of 20% ethanol/kg body wt IV every 4 hr for five treatments and then every 6 hr for four additional treatments) puppy needs 8.8 mL of ethanol per dose, 8.8 mL of ethanol per dose Which equates to 17.6 mL of 50% Vodka/dose, Ethanol in combination with 100 mg Vit B1 & 50 mg Vit B6 every 4-6 hrs, Glyoxalate and Oxalate (toxic metabolites) results in nephrotoxicity, 4-Methylpyrazole (4-MP, fomepizole) competitively metabolized by alcohol dehydrogenase, 4-MP (5% solution [50 mg/mL]) is 20 mg/kg body wt, IV, initially, followed by 15 mg/kg, IV, at 12 and 24 hr, and 5 mg/kg, IV, at 36 hr. dose 4-Methylpyrazole (4-MP, fomepizole), .5ml/ml needs to be converted to 8.8 mL of ethanol per dose, 4-MP (5% solution [50 mg/mL]) is 20 mg/kg body wt, IV, initially, followed by 15 mg/kg, IV, at 12 and 24 hr, and 5 mg/kg, IV, at 36 hr. ???? not available, Ethanol competitively metabolized by alcohol dehydrogenase, 50% Vodka as available alternative equivalent to .5ml/ml, Ethanol recommended treatment regimen (5.5 mL of 20% ethanol/kg body wt IV every 4 hr for five treatments and then every 6 hr for four additional treatments)