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This Concept Map, created with IHMC CmapTools, has information related to: Metabolism, Bactrim (Sulfamethoxazole/ Trimethoprim) caused (increased) change in levels of Warfarin in blood, change in levels of Warfarin in blood requires blood test to determine if levels are Normal, Zantac (Ranitidine) ???? increase bleeding, R-warfarin metabolized by CYP3A4, increased risk of bleeding when taken with S-warfarin, Bactrim (Sulfamethoxazole/ Trimethoprim) can cause increased risk of bleeding, CYP3A4 inhibited by Tagamet (Cimetidine), Prevacid (Lansoprazole) ???? increase bleeding, Low recommendation stop taking St. John's Wort, Amiodarone causes (increase) change in levels of Warfarin in blood, Xanax (alprazolam) metabolized by CYP3A4, St. John's Wort causes (decrease) change in levels of Warfarin in blood, Xanax (alprazolam) metabolized by CYP2C19, CYP3A4 inhibited by Zantac (Ranitidine), Tagamet (Cimetidine) ???? increase bleeding, Prilosec (Omeprazole) cost $20/42 tab, Coumadin (Warfarin) Stereoisomers R-warfarin, change in levels of Warfarin in blood requires blood test to determine if levels are High, High recommendation reduce warfarin strength, change in levels of Warfarin in blood requires blood test to determine if levels are Low