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This Concept Map, created with IHMC CmapTools, has information related to: Liver Function, Indirect Bilirubin (unconjugated) via UDP- Glucoronyl transferase Genetic Defects, Hepatocellular Injury consists of enzymes: AST, Biliary enzyme levels ???? GGT, phenobarbital CYP450 enzyme induction ????, Clotting Factors via coagulation tests INR, Rotor Syndrome Genetic Defects Conjugated Hyperbilirubinemia, Serum Proteins ???? Albumin, kernicterus encephalopathy death tx Calcium, Biliary enzyme levels ???? Alk Phos, Hepatocellular Function consist of clearance function, asymptomatic jaundice, N ASP ALT tx none, Drugs including Rifampin Probenecid Rifamycin, reduced UDP production Type II % production, no enzyme production symtoms kernicterus encephalopathy death, Calcium mechanism binds to bilirubin in GI tract, indicate Biliary tree patency Biliary enzyme levels, neonates physiologically Unconjugated Hyperbilirubinemia, Hepatocellular Function consist of synthetic function, mild jaundice tx phenobarbital, kernicterus encephalopathy death tx liver transplant