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This Concept Map, created with IHMC CmapTools, has information related to: Inflammation, Protein rich fluid accumulates in area ???? Oedema, Heat Increased Temp increases metabolic rate, Blood flow to injured area Effects Heat, Blood flow to injured area Effects Erythema, Chemicals for local effects (histamine, kinins, prostaglandins, leukatrienes, complement etc.) Effects Chemotaxis (attract WBC's to the area), Clotting proteins from blood escape into tissue spaces (eg. fibrinogen) ???? Blood clot (walling off effect), Leukocytosis inducing factor (systemic effect) Leukocytosis (increased production of WBC's) WBC's migrate to the injured area, WBC's cling to endothelium of capillary walls Diaphoresis Emigration - WBC's crawl through capillary wall, Chemotaxis (attract WBC's to the area) WBC's migrate to the injured area, Leak fluid (exudate) ???? Protein rich fluid accumulates in area, Leak fluid (exudate) ???? Clotting proteins from blood escape into tissue spaces (eg. fibrinogen), Tissue damage Release of Chemicals for local effects (histamine, kinins, prostaglandins, leukatrienes, complement etc.), Tissue damage Release of Leukocytosis inducing factor (systemic effect), Emigration - WBC's crawl through capillary wall ???? Puss may form, WBC's migrate to the injured area Margination WBC's cling to endothelium of capillary walls, Increased capillary permeability Capillaries Leak fluid (exudate), Puss may form ???? Area cleared of debris, Leak fluid (exudate) ???? Increased nutrients, O2 available for tissue repair, Vasodilation of blood vessels Increased Blood flow to injured area, Chemicals for local effects (histamine, kinins, prostaglandins, leukatrienes, complement etc.) Effects Increased capillary permeability