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This Concept Map, created with IHMC CmapTools, has information related to: Week 11-12_Myasthenia Gravis_ACh, voltage gated sodium channels lead to muscle contration, Mechanism for altered ACH action Decreases the number of nicotinic receptors available, adult: 1.8-3mg IV every 5 min doubling each time continued treatment give 10-20% dose hourly 1-2 weeks, Mechanism for altered ACH action Replace ACh-like drug (resistant to ACh-esterase), child: 0.05 - 0.1mg/kg IV every 5 min doubling each time endpoint obvious atropinization, Acetylcholine Measuring ACh in neuromuscular junction by Train of four, M1-5 leads to cholinergic syndrome increased defecation, Edrophonium effects Reversal of muscle relaxation, atropine muscarinic effects blocks muscarinic receptors, overdose effects delirium, Myasthenia Gravis Symptoms Include Drooping position of head, Myasthenia Gravis Symptoms Include Facial paralysis, IV 5mg/10mL administer 10mL, Depolarizing Blocker example Succinylcholine, Organophosphate Poisoning Treatment oximes, Mechanism for altered ACH action Blocks release from nerve ending, ACh binding to esterase reversible example neostigmine, the number of nicotinic receptors available example Myasthenia Gravis, overdose effects hot, Mechanism for altered ACH action Blocks ACh binding to esterase reversible