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This Concept Map, created with IHMC CmapTools, has information related to: Malaria-Guelph2010, Different Species of Plasmodium the most widespread P. Vivax, Tumour Necrosis Factor (TNF) increases effects of severe malarial anaemia, Different Species of Plasmodium the strain with the mildest symptoms P. Malariae, Interleukin 10 polymorphisms increases risk of severe malaria, nausea, fatigue, headache, anorexia evolves into fever, more severe headache nausea & vomitting with upper abdominal pain, Different Species of Plasmodium ???? Ovale, Tumour Necrosis Factor (TNF) automatic immune response proinflammatory, Immune Response ???? Cytokines, Different Species of Plasmodium the most recently discovered P. Knowlesi, reasons severity of malaria differs based on ???? Form of Malaria, Form of Malaria genetic factor P. falciparum, The Severity of Malaria ???? reasons severity of malaria differs based on, var gene family increases virulence of P.falciparum makes proteins that migrate to outer surface of red blood cells so they can attach to body cavities, Patients genectic factors Blood Type, reasons severity of malaria differs based on ???? Patients, P. falciparum initially manifests as nausea, fatigue, headache, anorexia, Blood Type ???? O, Tumour Necrosis Factor (TNF) increases effects of cerebral malaria, P. falciparum Infects Largest % RBCs, Cytokines ???? Tumour Necrosis Factor (TNF)