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This Concept Map, created with IHMC CmapTools, has information related to: infection of bone, vascularity of bone insufficiency diabeties, Pseudomonas from puncture wounds, salmonella from children with sickle cell anemia, osteomyelitis symptoms fever chills swelling erythema, underlying disease bactoremia hematogenous seeding, osteomyelitis pathogenesis factors age, location internal body hardware leads to biofilm, hematogenous seeding where most common vertebrae, S. aureus virulence factors bacterial adherence (pili), trauma ???? fracture wound, Escherichia coli from puncture wounds, osteomyelitis pathogenesis factors compromised immune system, osteomyelitis treat debridement (incision/drainage), osteomyelitis pathogenesis factors underlying disease, gram-neg organisms des. bacilli anaerobic, diabeties inadequate local tissue resp., leads to biofilm treat with rifampicin and anti- biotic, cephalosporin oxacillin/nafcillin (beta-lactam) clindamycin ???? methicillin-susceptible Staphylococcus Aureus, age secondary adult metaphyseal, trauma ???? IV drug use