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This Concept Map, created with IHMC CmapTools, has information related to: Antibiotics, Doxycyclin treats chlamidia, Inactivating enzymes e.g beta-lactamase Aminoglycoside-modifying enzyme, Antibiotics sites of action inhibit DNA syn, beta-lactamase Aminoglycoside-modifying enzyme resists beta-lactam MRSA, Fluoroquinolones resists TB treatment (mutations) XDR-TB, Antibiotics mechanism of resistance Antibiotic target modification, inhibit RNA polymerase e.g Rifampin, inhibit DNA syn e.g Fluoroquinolones, Antibiotic target modification e.g Altered penicillin binding proteins Altered DNA gyrase (releives stress), Penicillins Cephalosporins Carbapenems Glycopeptides (vancomycin) beta-lactam resists beta-lactam MRSA, Antibiotics sites of action inhibit cell wall syn (transpeptidase), Antibiotics mechanism of resistance Efflux pump, Antibiotics sites of action bind to ribosomes inhibit protein syn, inhibit cell wall syn (transpeptidase) e.g Penicillins Cephalosporins Carbapenems Glycopeptides (vancomycin) beta-lactam, Rifampin resists TB treatment (mutations) XDR-TB, cephalosporins insensitive beta lactamase, Antibiotics mechanism of resistance Inactivating enzymes, bind to ribosomes inhibit protein syn e.g Aminoglycosides Tetracyclines Macrolides Clindamycin Chloramphenicol Linezolid Azithromycin, Antibiotics sites of action inhibit RNA polymerase, Antibiotics mechanism of resistance Permeability barriers