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This Concept Map, created with IHMC CmapTools, has information related to: pathogenesis, ability to cause disease measured by Virulence Factors (capsules exotoxins endotoxins), inflammation evade intracellular survival, NO (from macrophages) leads to spetic shock, streptococcus pyogenes secretes hyaluronidase, Endotoxins not secreted, human indirect vector (bug), human mainly zoonoses, Mycobacterium tuberculosis consists CD4-positive T cells, characteristic features of disease appear ???? specific-illness, disease types pandemic, Exotoxins several actions superantigens, Pathogenesis microbes causing virulence, cytokines ex IL-1, Exotoxins modified to produce nontoxic toxoids, communicable human to human, glycocalyx strong adherance heart valves prosthetic implants catheters, lipopolysaccharides (LPS) toxic component Lipid A, lipopolysaccharides (LPS) activates coagulation cascade, Endotoxins are poorly antigenic, Lipid A overproduce cytokines